Vía metabólica de la dislipidemia en la hipertensión arterial. Artículo de revisión
Metabolic pathway of dyslipidemia in arterial hypertension. Review article
Keywords:
Hypercholesterolemia, nitric oxide, dysfunction, endothelial, renin-angiotensin system, hypertensionAbstract
Arterial hypertension (hypertension) and atherosclerosis are closely linked and in this relationship the renin-angiotensin system (ARS) plays a leading role, since it participates in the progression of vascular disease. The objective of this study was to present a review of the molecular and cellular pathophysiological mechanisms of the effect of lipoproteins on the genesis of HT. The search strategy included review and observational studies, systematic review and meta-analysis of the biomedical literature about biochemical and physiological aspects associated with hypertension, with the following search terms: obesity and overweight, high blood pressure, dyslipidemia, endothelial dysfunction, resistance to insulin and diabetes mellitus. To this end, a search was conducted between March and October 2018 in the LILACS, MEDLINE-PubMed and Cochrane Library databases. Results and conclusions the detection of endothelial dysfunction in people
with arterial hypertension has prognostic and therapeutic importance, since it allows the intensity of the treatment needed to avoid complications. The correction of endothelial dysfunction can be considered an objective of treatment to try to stop the atherosclerotic process and improve the prognosis. The behavior must be integral to include the different pathophysiological, hemodynamic and metabolic aspects involved in the health-disease process of each individual.
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Azcona ÁC. Universidad Complutense de Madrid. Facultad de Farmacia.Departamento de nutricion. [Online].; 2013 [cited 2017 12 24. Available from: https://www.ucm.es/data/cont/docs/458-2013-07-24-cap-6-grasas.pdf.
O’Donne CJ, Elosua. Factores de riesgo cardiovascular. Perspectivas derivadas del Framingham Heart Study. Revista Epañola de Cardilogia. 2008; 61(3).
Monteiro Junqueira AS, Martins Romêo LJ, Carneiro Junqueira CdLCJ. Evaluación del grado de inflamación vascular pacientes con síndrome metabólico. Arq Bras Cardiol. 2009; 93(4).
LAMAS , HERNÁNDEZ PERERA O. Disfunción endotelial en la aterosclerosis: papel protector de las estatinas. Nefrologia. 1998; 18(51).
Baynes J. Bioquímica Médica. Cuarta ed. Edición D, editor. Barcelona: Elevesier España, S.L.U.; 2014.
Campbell M, Farrell S. Bioquímica. Octava ed. Vega A, editor. México: Cengage Learning; 2016.
Castillo J, Oscanoa T. Redalyc. [Online].; 2016 [cited 2017 Diciembre 26. Available from: http://www.redalyc.org/pdf/3716/371649170003.pdf.
Carrasco DF, Galgani DJ, Reyes DM. Sindrome de resistencia a la insulina. Estudio y manejo. Revista medica condes. 2013 Jul;(24(5) 827-837]).
Carbajal A. Universidad Complutense de Madrid, Manual de nutricion y dieta. [Online].; 2013 [cited 2017 12 24. Available from: https://www.ucm.es/data/cont/docs/458-2013-0724-cap-6-grasas.pdf.
Castro-Torres IG. Formación de cálculos biliares de colesterol. Nuevos avances científicos. Scielo. 2012 Marzo; 66(1).
Costanzo LS. Fisiologia. 5th ed. Fotoletra SA, editor. España: Elseiver España; 2014.
Devlin T. Bioquímica con aplicaciones clínicas. Cuarta ed. Wiley J, editor. Barcelona: Editorial Reverté; 2015.
Feduchi E, Blasco I, Romero C, Yánez E. Bioquímica conceptos esenciales Madrid: Editorial Médica Panamericana; 2014.
Ferrier DR. Bioquimica. 6th ed. Harvey RA, editor. Mexico: Wolters Kluwer ; 2014.
Hall JE. Fisiologia medica de Guyton y Hall. 13th ed. USA: Elseiver; 2016.
Acevedo M, Kramer V, Tagle R, Corbalan R, Arnaiz P, Berrios X, et al. Relación colesterol total a HDL y colesterol no HDL: los mejores indicadores lipídicos de aumento de grosor de la íntima media carotidea. Revista medica de Chile. Scielo. 2012 Agosto ; 140(18).
Arellano O, Bárquera S, Barriguete J, Lara A, López A, Rosas M. Secretaría de Salud México. [Online].; 2015 [cited 2017 Diciembre 27. Available from: https://www.gob.mx/cms/uploads/attachment/file/18734/ProtocoloClinico_diagnostico_tratamiento_dislipidemias.pdf.
Canalizo E, Favela E, Salas J, Gómez R, Jara R, Del Pilar L, et al. medigraphic literatura biomédica. [Online].; 2013 [cited 2017 Diciembre 27. Available from: http://www.medigraphic.com/pdfs/imss/im-2013/im136t.pdf.
Diaz DJ. Bases medicina. Dislipidemias. [Online]. [cited 2017 12 24. Available from: http://www.basesmedicina.cl/nutricion/606_dislipidemias/66_nutricion_dislipidemias.pdf.
Institute UoOH. The role of phospholipids in the biological activity and structure of the endoplasmic reticulum. NCBI. Publmed.gov. 2013 May;(2499-510).
Garcia LA, Arce EC. Controversias actuales sobre las lipoproteínas de alta densidad. Correo cientifico medico. Scielo. 2015 enero-marzo; 29(1).
Errico T, Chen X, Campos M, Julve J, Carles J, Blanco F. Elsevier. [Online].; 2013 [cited 2017 Diciembre 25. Available from: http://www.elsevier.es/es-revista-clinica-einvestigacion-arteriosclerosis-15-pdf-S0214916813000314-S300.
Gaw A, Colaboradores. Bioquimica clinica. 5th ed. Espana: Elseiver; 2015.
Horton HR, Moran LA, Scrimgeour G, Perry MD, David R. Principios de bioquimica. 4th ed. Mexico : Pearson; 2008.
Kreisberg R, Leiter L. Hormone Health Network. [Online].; 2012 [cited 2017 Diciembre Available from: https://www.hormone.org/~/media/hormone/files/spanish/questions-andanswers/heart-health/fs_cmd_hyperlipidemia_sp-612.pdf.
Arocha Rodulfo , López Góme uE, Amair , Octavio JA. Hipertensión arterial y dislipidemia, una dupla de peligro. Revista cientifica de la sociedad Venezolana de Cardilogia. 2017; 37(3).
Martinez Dy. Endocrinologia clinica. 5th ed. Tripp DNG, editor. Mexico : El manual moderno S.A de C.V; 2015.
Lieberman M. Bioquimica medica basica. 4th ed. LW& W, editor. Mexico : Wilkins; 2013.
Maldonado O, Ramírez I, García R, Ceballos G, Méndez E. Scielo. [Online].; 2012 [cited 2017 12 24. Available from: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1870-01952012000200002.
Mckee T, McKee J. Bioquímica, las bases moleculares de la vida. Quinta ed. de León J, editor. México: McGRAW-HILL Companies, Inc.; 2014.
Arrebola-Moreno AL, Laclaustra , Kaski JC. Evaluación no invasiva de la función endotelial en la práctica clínica. Revista Española de Cardiología. 2012; 65(1).
Merchán A. ScienceDirect. [Online].; 2016 [cited 2017 Diciembre 25. Available from: https://www.sciencedirect.com/science/article/pii/S0120563316300444.
Micocci L. Universidad Nacional del Litoral. Quimica biologica. [Online].; 2018 [cited 2017 12 24. Available from: http://www.unl.edu.ar/ingreso/cursos/medicina/wp-content/uploads/sites/8/2017/10/Quimica_09.pdf.
Mulroney SE, Myres AK. Netter fundamentos de fisiologia. 2nd ed. España E, editor. España : Elsevier; 2016.
Morejón O, Triana M. Scielo. [Online].; 2015 [cited 2017 Diciembre 24. Available from: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1682-00372015000100008.
Palmett-Rios HE. Estudio transversal sobre estilos de vida saludable y su relacion con el colesterol HDL en la poblacion adulta. Scielo. 2017 Agosto ; Vol.24(N°5).
Murray R, Bender D, Botham K, Rodwell P, Weil A. Harper Bioquímica Ilustrada. Vigésima novena ed. de León J, editor. México: The McGRAW-HILL Companies, Inc.; 2012.
Rodríguez L, Fernández J, Díaz M, Ruiz V, Hernández H, Vivian H, et al. bvsCuba. [Online].; 2014 [cited 2017 Diciembre 26. Available from: http://www.bvs.sld.cu/revistas/ped/vol86_4_14/ped04414.htm.
Piñeiro R, Fernández J, Gómez I. Scielo. [Online].; 2012 [cited 2017 Diciembre Available from: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S086403002012000100004&nrm=iso.
Vidal R. Sociedad Española de Cardiolgía. [Online].; 2015 [cited 2017 Diciembre Available from: https://secardiologia.es/multimedia/blog/5965-efecto-de-la-hiperlipidemiaen-el-tiempo-tratar-cuanto-antes-mejor.
Barret KE, Barman SM, Boitano S, Brooks H. Ganong Fisiologia Medica. 24th ed. C.V MHISAd, editor. Mexico : McGraw-Hill; 2013.
Picinin AA, Lopes GC. Nutraceuticos no manejo das dislipidemias: Terepia baseada em evidencia. Revista Uningá Review. 2018 Junio ; 29(1).
Renterias IB. Diabetes, obesidad y sindrome metabolico Moderno EM, editor.: Editorial El Manual Moderno; 2015.
Torres J, Duran S. Fosfolipidos: propiedades y efectos en la salud. Nutricion hospitalaria. 2015 Sep; 31(76-83).
Silvestri C, DiMarzo V. The endocannabinoid system in energy homeostasis and the etiopathology of metabolic disorders. NCBI.Publmed.gov. 2013 Abril;(2;17(4):475-90).
Berge K PFHNSCMIBSDMV. Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men. Pubmed. 2013 Mayo;( 27;12:78).
Sánchez DLGC, Garcés DE. Factores de riesgo de la cardiopatía isquémica. Revista Cubana de Medicina General Integral. 2013 oct-dic; Vo.29(N.4).
Tolosa A. MicroARNs y metabolismo del colesterol. Genetica medica News. 2015 Noviembre. ISSN 1390-910X Páginas 76 - 86
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